Sunday, April 21, 2013

Memory can be strengthened molecular and cellular training schemes

Память можно укрепить молекулярно-клеточными обучающими схемами    Not so long ago researchers from the Texas university in Houston (USA) found out that neurons remember information better if to adhere to a certain schedule of training incentives. Storing, as we know, depends on synthesis of certain proteins in nervous cages. In this case for the second incentive it is possible to pick up such time when the new wave of activation of genes will enter, so to speak, in a resonance with a wave from the previous incentive and will improve storing. Differently, will improve a "zapominatelny" proteinaceous profile in a cage. On the basis of data on gene and proteinaceous dynamics scientists constructed mathematical model which allowed to develop "the schedule of lessons" for neurons.
Нейробиолог Джон Бирн с коллегами и морским зайцем (фото The University of Texas Health Science Center at Houston).

Neurobiologist John Byrne with colleagues and a sea hare (a photo of The University of Texas Health Science Center at Houston).

    In a new series of experiments the same scientific group under the leadership of John Byrne tried to promote by means of such obuchayushche-stimulating technique slightly further and to prevent memory impairment. As well as in the previous work, experiment was made with cages of a mollusk of Aplysia californica (he is a sea hare), which nervous system thanks to the large and multi-colored neurons often acts as model object in neurobiological researches.

   To simulate memory impairment, culture of nervous cages processed the substance weakening contacts between neurons. It is known that storing depends on exchange of information between nervous cages therefore durability of memory, especially long-term, is defined by firmness of interneural connections. To simulate training, other substance which raised neurons was used. "Training sessions" with culture of cages were carried out according to the schemes calculated by means of the mathematical program on the basis of the schedule of molecular and biochemical processes in neurons. Different schemes provided different and irregular intervals between incentives, from 5 to 50 minutes.

   As researchers write to "educational schemes" to Journal of Neuroscience, after five "training sessions", carried out on such, connection force between neurons was restored. And it is worth emphasizing once again that scientists used not medicine, and simply irritating substance. That is systematic exercises in itself are capable to have beneficial impact on memory, returning to neurons the former force of contact. The schemes created by authors of work, not simply help memory, but also treat her for damages.

   Whether it is possible to use this method at disorders of memory at the person? His authors consider that is possible, but it is necessary to modify technology according to human neurochemical features. After all the sense consists not so much in in itself intellectual exercises, how many in their schedule, distribution in time. And to make such schedule effective for the person, it is necessary that it corresponded to waves of molecular and genetic activity in our neurons.

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